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团队发表文章

2021-2022 年

2021年度代表性文章:


  1. Cui, J.Q., Cui, P.F., Shi, J.Z., Fan, W.F., Xing, X., Gu, W.L., Zhang, Y.C., Zhang, Y.P., Zeng, X.Y., Jiang, Y.P., Chen, P.C., Yang, H.L., Chen, Y., Liu, J.X., Liu, L.L., Tian, G.B., Lu, Y.X., Chen, H.L., Li, C.J., Deng, G.H., 2021. Continued evolution of H6 avian influenza viruses isolated from farms in China between 2014 and 2018. Transbound Emerg Dis doi: 10.1111/tbed.14212.

  2. Fan, M.L., Liang, B., Zhao, Y.Z., Zhang, Y.P., Liu, Q.Z., Tian, M., Zheng, Y.Q., Xia, H.Z., Suzuki, Y., Chen, H.L., Ping, J.H., 2021. Mutations of 127, 183 and 212 residues on the HA globular head affect the antigenicity, replication and pathogenicity of H9N2 avian influenza virus. Transbound Emerg Dis, doi: 10.1111/tbed.14363.

  3. Guo, J., Wang, Y.W., Zhao, C.H., Gao, X.X., Zhang, Y.P., Li, J.Q., Wang, M.J., Zhang, H., Liu, W.Q., Wang, C., Xia, Y.J., Xu, L., He, G.M., Shen, J.Y., Sun, X.H., Wang, W.T., Han, X.Y., Zhang, X.X., Hou, Z.Y., Jin, X.L., Peng, N., Li, Y.B., Deng, G.H., Cui, P.F., Zhang, Q.Y., Li, X.Y., Chen, H.L., 2021. Molecular characterization, receptor binding property, and replication in chickens and mice of H9N2 avian influenza viruses isolated from chickens, peafowls, and wild birds in eastern China. Emerg Microbes Infec 10, 2098-2112.

  4. Kong, X.T., Guan, L.Z., Shi, J.Z., Kong, H.H., Zhang, Y.P., Zeng, X.Y., Tian, G.B., Liu, L.L., Li, C.J., Kawaoka, Y., Deng, G.H., Chen, H.L., 2021. A single-amino-acid mutation at position 225 in hemagglutinin attenuates H5N6 influenza virus in mice. Emerg Microbes Infec 10, 2052-2061.

  5. Li, C.J., Chen, H.L., 2021. H7N9 Influenza Virus in China. Csh Perspect Med 11.

  6. Li, J.P., Liang, L.B., Jiang, L., Wang, Q., Wen, X., Zhao, Y.H., Cui, P.F., Zhang, Y.P., Wang, G.W., Li, Q.B., Deng, G.H., Shi, J.Z., Tian, G.B., Zeng, X.Y., Jiang, Y.P., Liu, L.L., Chen, H.L., Li, C.J., 2021a. Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission. Plos Pathog, 17(2):e1009336.

  7. Li, Y.L., Li, M.H., Tian, J.M., Bai, X.L., Li, Y.B., 2021. Genetic characteristics and pathogenicity of novel reassortant H6 viruses isolated from wild birds in China. Vet Microbiol 254:108978.

  8. Qu, Z.Y., Meng, F., Shi, J.Z., Deng, G.H., Zeng, X.Y., Ge, J.Y., Li, Y.B., Liu, L.L., Chen, P.C., Jiang, Y.P., Li, C.J., Chen, H.L., 2021. A Novel Intronic Circular RNA Antagonizes Influenza Virus by Absorbing a microRNA That Degrades CREBBP and Accelerating IFN-beta Production. Mbio 12(4):e0101721.

  9. Song, Y.M., Huang, H.X., Hu, Y.Z., Zhang, J.W., Li, F., Yin, X., Shi, J.Z., Li, Y.B., Li, C.J., Zhao, D.M., Chen, H.L., 2021. A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis. Plos Pathog 17(12):e1010141.

  10. Tian, J., Li, M., Bai, X., Li, Y., Wang, X., Wang, F., Shi, J., Zeng, X., Tian, G., Li, Y., 2021. H5 low pathogenic avian influenza viruses maintained in wild birds in China. Vet Microbiol 263, 109268.

  11. Wang, Z., Chen, Y., Chen, H.Y., Meng, F., Tao, S.Y., Ma, S.J., Qiao, C.L., Chen, H.L., Yang, H.L., 2021. A single amino acid at position 158 in haemagglutinin affects the antigenic property of Eurasian avian-like H1N1 swine influenza viruses. Transbound Emerg Dis doi: 10.1111/tbed.14288.

  12. Yin, X., Deng, G.H., Zeng, X.Y., Cui, P.F., Hou, Y.J., Liu, Y.J., Fang, J.Z., Pan, S.X., Wang, D.X., Chen, X.H., Zhang, Y.P., Wang, X.R., Tian, G.B., Li, Y.B., Chen, Y., Liu, L.L., Suzuki, Y., Guan, Y.T., Li, C.J., Shi, J.Z., Chen, H.L., 2021. Genetic and biological properties of H7N9 avian influenza viruses detected after application of the H7N9 poultry vaccine in China. Plos Pathog 17(4):e1009561.


2022年度代表性文(截止2022年7月1日)


  1. Cui, P., Shi, J., Wang, C., Zhang, Y., Xing, X., Kong, H., Yan, C., Zeng, X., Liu, L., Tian, G., Li, C., Deng, G., Chen, H., 2022a. Global dissemination of H5N1 influenza viruses bearing the clade 2.3.4.4b HA gene and biologic analysis of the ones detected in China. Emerg Microbes Infect 11, 1693-1704.

  2. Cui, P., Zeng, X., Li, X., Li, Y., Shi, J., Zhao, C., Qu, Z., Wang, Y., Guo, J., Gu, W., Ma, Q., Zhang, Y., Lin, W., Li, M., Tian, J., Wang, D., Xing, X., Liu, Y., Pan, S., Zhang, Y., Bao, H., Liu, L., Tian, G., Li, C., Deng, G., Chen, H., 2022. Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China. Sci China Life Sci 65, 795-808.

  3. Gu, W., Shi, J., Cui, P., Yan, C., Zhang, Y., Wang, C., Zhang, Y., Xing, X., Zeng, X., Liu, L., Tian, G., Suzuki, Y., Li, C., Deng, G., Chen, H., 2022. Novel H5N6 reassortants bearing the clade 2.3.4.4b HA gene of H5N8 virus have been detected in poultry and caused multiple human infections in China. Emerg Microbes Infect 11, 1174-1185.

  4. Guo, J., Chen, J., Li, Y., Li, Y., Deng, G., Shi, J., Liu, L., Chen, H., Li, X., 2022. SUMOylation of Matrix Protein M1 and Filamentous Morphology Collectively Contribute to the Replication and Virulence of Highly Pathogenic H5N1 Avian Influenza Viruses in Mammals. J Virol 96, e0163021.

  5. Wan, X., Li, J., Wang, Y., Yu, X., He, X., Shi, J., Deng, G., Zeng, X., Tian, G., Li, Y., Jiang, Y., Guan, Y., Li, C., Shao, F., Chen, H., 2022. H7N9 virus infection triggers lethal cytokine storm by activating gasdermin E-mediated pyroptosis of lung alveolar epithelial cells. National science review 9, nwab137.

  6. Wang, G., Zhao, Y., Zhou, Y., Jiang, L., Liang, L., Kong, F., Yan, Y., Wang, X., Wang, Y., Wen, X., Zeng, X., Tian, G., Deng, G., Shi, J., Liu, L., Chen, H., Li, C., 2022a. PIAS1-mediated SUMOylation of influenza A virus PB2 restricts viral replication and virulence. Plos Pathog 18, e1010446.

  7. Wang, Y., Wang, M., Zhang, H., Zhao, C., Zhang, Y., He, G., Deng, G., Cui, P., Li, Y., Liu, W., Shen, J., Sun, X., Wang, W., Zeng, X., Li, Y., Chu, D., Peng, P., Guo, J., Chen, H., Li, X., 2022. Emergence, Evolution, and Biological Characteristics of H10N4 and H10N8 Avian Influenza Viruses in Migratory Wild Birds Detected in Eastern China in 2020. Microbiology spectrum 10, e0080722.

  8. Zeng X, He X, Meng F, Ma Q, Wang Y, Bao H, Liu Y, Deng G, Shi J, Li Y, Tian G, Chen H*. 2022. Protective efficacy of an H5/H7 trivalent inactivated vaccine (H5-Re13, H5-Re14, and H7-Re4 strains) in chickens, ducks, and geese against newly detected H5N1, H5N6, H5N8, and H7N9 viruses. Journal of Integrative Agriculture, 21(7):2086–2094.

  9. Zhao, C., Guo, J., Zeng, X., Shi, J., Deng, G., Zhang, Y., Wang, Y., Ma, Q., Gao, X., Cui, P., Liu, L., Li, X., Chen, H., 2022. Novel H7N7 avian influenza viruses detected in migratory wild birds in eastern China between 2018 and 2020. Microbes and infection, 105013.


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