孔晖晖，中国共产党党员，博士生导师，中国农业科学院哈尔滨兽医研究所研究员，中国农业科学院优秀青年英才。兼任中国畜牧兽医学会动物传染病学分会青年委员和中国疾病预防控制中心周报青年编委。长期从事流感病毒的防控研究，包括跨种感染、抗原变异、广谱疫苗及治疗策略等。围绕动物流感综合防控重大需求，构建了从跨种传播机制解析、抗原变异智能预测到疫苗和治疗技术研发的系统性研究体系。系统揭示了流感病毒跨种感染与传播的分子机制，创新建立抗原变异研究方法并研发全球首个甲型流感抗原预测与可视化一体化平台 FluNexus；面向 H5N1 奶牛流感等新发疫情风险，创制奶牛专用灭活、DNA 和 mRNA 三类疫苗，并开发 Nb-PROTAC 靶向降解抗病毒平台，在广谱抗流感病毒防控研究方面取得系列创新突破。相关研究成果以第一或通讯（含共同）作者身份，在 Cell Research、Signal Transduction and Targeted Therapy、Cell Host & Microbe、iMeta、National Science Review 等高水平 SCI 期刊发表论文 20 篇。主持“十四五”国家重点研发计划青年科学家项目、国家自然科学基金青年项目、黑龙江省自然科学基金杰出青年项目等多项科研项目。 

代表论文与著作：

1. Zhuang, Y., Chen, L., Qin, C., Chen, P., Feng, L., Lin, W., Li, J., Zhang, Y., Wang, C., Shi, J., Deng, G., Zeng, X., Cui, P., Li, Y., Jiang, Y., Chen, H., Kong, H. A nanobody-based proteolysis-targeting chimera offers broad-spectrum protection against diverse influenza virus infections. Signal Transduction and Targeted Therapy, 2026, 11.（通讯作者；IF: 81.2）

2. Li, X., Zhou, C., Wu, H., Xiao, K., Hao, J., Zhao, D., Deng, G., Li, Y., Gu, J., Cai, W., Zhu, J., Peng, J., Li, M., Liu, Y., Shang, X., Chen, H., Kong, H. FluNexus: A versatile web platform for antigenic prediction and visualization of influenza A viruses. iMeta, 2026, 5, e70127.（通讯作者；IF: 44.4）

3. Kong, H., Yang, J., Shi, J., Cui, P., Zeng, X., Liu, W., He, X., Zhang, X., Chen, L., Zhuang, Y., Wang, Y., Ma, J., Li, J., Zhang, Y., Wang, C., He, C., Li, J., Yang, J., Liu, J., Chen, P., Guan, Y., Bu, Z., Jiang, Y., Chen, H. Protective Efficacy of a Hemagglutinin-Based mRNA Vaccine Against H5N1 Influenza Virus Challenge in Lactating Dairy Cows. Research, 2026, 9, 1104.（第一作者；IF: 12.9）

4. Wang, X., Kong, H., Chu, B., Yang, Q., Lin, C., Liu, R., Chen, C., Gao, Y., Wang, G., Wang, D., Qin, C., Ye, X., Yu, L., Xu, X., Jin, J., Sun, R., Chen, H., Wu, X., Zhang, Z. Identification of a broad-inhibition influenza neuraminidase antibody from pre-existing memory B cells. Cell Host & Microbe, 2025, 33, 151-166 e158.（共第一；IF: 20.6）

5. Shi, J., Kong, H., Cui, P., Deng, G., Zeng, X., Jiang, Y., He, X., Zhang, X., Chen, L., Zhuang, Y., Wang, Y., Ma, J., Li, J., Zhang, Y., Wang, C., He, C., Yang, J., Li, J., Liu, W., Yang, J., Mao, S., Liu, J., Chen, P., Tian, G., Li, C., Guan, Y., Bu, Z., Chen, H. H5N1 virus invades the mammary glands of dairy cattle through 'mouth-to-teat' transmission. National Science Review, 2025, 12, nwaf262.（共第一；IF: 17.1）

6. Zhang, Y., Cui, P., Shi, J., Zeng, X., Jiang, Y., Chen, Y., Zhang, J., Wang, C., Wang, Y., Tian, G., Chen, H., Kong, H., Deng, G. A broad-spectrum vaccine candidate against H5 viruses bearing different sub-clade 2.3.4.4 HA genes. npj Vaccines, 2024, 9, 152.（共通讯；IF: 6.6）

7. Cui, P., Zhuang, Y., Zhang, Y., Chen, L., Chen, P., Li, J., Feng, L., Chen, Q., Meng, F., Yang, H., Jiang, Y., Deng, G., Shi, J., Chen, H., Kong, H. Does pasteurization inactivate bird flu virus in milk? Emerging Microbes & Infections, 2024, 13, 2364732.（通讯作者；IF: 8.4）

8. Sun, L., Kong, H., Yu, M., Zhang, Z., Zhang, H., Na, L., Qu, Y., Zhang, Y., Chen, H., Wang, X. The SUMO-interacting motif in NS2 promotes adaptation of avian influenza virus to mammals. Science Advances, 2023, 9, eadg5175.（共第一；IF: 11.7）

9. Kong, H., Fan, S., Takada, K., Imai, M., Neumann, G., Kawaoka, Y. H3N2 Influenza Viruses with 12- or 16-Amino Acid Deletions in the Receptor-Binding Region of Their Hemagglutinin Protein. mBio, 2021, 12, e0151221.（第一作者；IF: 7.8）

10. Kong, H., Burke, D. F., da Silva Lopes, T. J., Takada, K., Imai, M., Zhong, G., Hatta, M., Fan, S., Chiba, S., Smith, D., Neumann, G., Kawaoka, Y. Plasticity of the Influenza Virus H5 HA Protein. mBio, 2021, 12.（第一作者；IF: 7.8）

11. Kong, H., Ma, S., Wang, J., Gu, C., Wang, Z., Shi, J., Deng, G., Guan, Y., Chen, H. Identification of Key Amino Acids in the PB2 and M1 Proteins of H7N9 Influenza Virus That Affect Its Transmission in Guinea Pigs. Journal of Virology, 2019, 94.（第一作者；IF: 5.1）

12. Shi, J., Deng, G., Kong, H., Gu, C., Ma, S., Yin, X., Zeng, X., Cui, P., Chen, Y., Yang, H., Wan, X., Wang, X., Liu, L., Chen, P., Jiang, Y., Liu, J., Guan, Y., Suzuki, Y., Li, M., Qu, Z., Guan, L., Zang, J., Gu, W., Han, S., Song, Y., Hu, Y., Wang, Z., Gu, L., Yang, W., Liang, L., Bao, H., Tian, G., Li, Y., Qiao, C., Jiang, L., Li, C., Bu, Z., Chen, H. H7N9 virulent mutants detected in chickens in China pose an increased threat to humans. Cell Research, 2017, 27, 1409-1421.（共第一；IF: 25.6）

13. Zhang, Y., Zhang, Q., Kong, H., Jiang, Y., Gao, Y., Deng, G., Shi, J., Tian, G., Liu, L., Liu, J., Guan, Y., Bu, Z., Chen, H. H5N1 hybrid viruses bearing 2009/H1N1 virus genes transmit in guinea pigs by respiratory droplet. Science, 2013, 340, 1459-1463.（IF: 47.7）