Ilyas Khan, Male, Ph.D., Postdoctoral Researcher. His research focuses on the molecular mechanisms of coronavirus and filovirus entry, particularly the regulation of endosomal viral fusion by host factors. By integrating experimental virology with proteomics, structural biology, and computational analyses, he investigates the role of Niemann–Pick C1 (NPC1) in virus–host interactions and develops host-targeted broad-spectrum antiviral strategies. His work has led to the identification of Tubeimosides as pan-coronavirus and filovirus inhibitors targeting NPC1-mediated viral entry. He has published as first author or co-first author in internationally recognized SCI journals, including Nature Communications, mBio, and BMC Complementary Medicine and Therapies, and as a co-author in Advanced Science and other high-impact journals.

1、Contact information

Research direction: Veterinary microbiology and molecular biology

Phone：0451-51051761/18182819530

Mailbox：ilyas_microbiologist@yahoo.com

Mailing address： No. 678 Haping Road, Xiangfang District, Harbin City, Heilongjiang Province

2、Educational background

2019.03-2024.06  PhD in Preventive Veterinary Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences

2013.11-2015.12  Master's degree in Microbiology, Kohat University of Science and Technology, Kohat, Pakistan

2008.11-2013.03  Bachelor's degree in Microbiology, Kohat University of Science and Technology, Kohat, Pakistan

3、Work experience

2024.07-Present: Postdoctoral researcher at Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences

4、Representative papers and publications

1) Ilyas Khan, Sunan Li, Lihong Tao, Chong Wang, Bowei Ye, Huiyu Li, Xiaoyang Liu, Iqbal Ahmad, Wenqiang Su, Gongxun Zhong, Zhiyuan Wen, Jinliang Wang, Rong-Hong Hua, Ao Ma, Jie Liang, Xiao-Peng Wan, Zhi-Gao Bu & Yong-Hui Zheng. Tubeimosides are pan-coronavirus and filovirus inhibitors that can block their fusion protein binding to Niemann-Pick C1.  Nature Communications, (2024).

2) Ilyas Khan, Usman Ali Khan, Taj Ali Khan, Abdul Tawab, Anwar Hussain, Mohammad Qasim, Muhammad Adnan, Azizullah Azizullah, waheed Murad, Abdullah Jalal, Nawab Ali,” Punica granatum peel extracts: HPLC fractionation and LC MS/MS analysis for bioactive compounds identification”, BMC Complementary and Alternative Medicine, (2017) 17:247.

3) Hazir Rahman*, Ilyas Khan*, Anwar Hussain; Abdelaaty Abdelaziz Shahat; Abdul Tawab; Muhammad Qasim; Muhammad Adnan; Mansour S Al-Said; Riaz Ullah; Shahid Niaz Khan, “Glycyrrhiza glabra HPLC fractions: Identification of Aldehydo Isoophiopogonone and Liquirtigenin having activity against multidrug resistant bacteria”, BMC Complementary and Alternative Medicine, (2018) 18:140.