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首席科学家

1、个人简历

王靖飞,男,博士,研究员,中国农业科学院哈尔滨兽医研究所博士生导师、 东北农业大学兽医专业硕士生导师,动物病原与病理形态学研究创新团队首席科学家,国家动物疫病数据中心副主任,中国畜牧兽医学会信息技术分会副理事长,中国农业部/FAO“中国兽医现场流行病学培训项目(FETPV)”导师,中国畜牧兽医学会高级会员。在国内外杂志发表研究论文50余篇;出版专著4部;注册软件5部;获省部级奖励5项;主持课题10余项。目前主要从事基于冷冻电镜的动物病毒结构解析、病毒基因组学分析、病理及超微病理学及动物疫病流行趋势建模等相关研究。
 
2、联系方式
(1)研究方向:动物传染病及其病原分子流行病学
(2)电话:0451-51051770
(3)邮箱:wangjingfei@caas.cn
(4)通讯地址:黑龙江省哈尔滨市香坊区哈平路678号,150069
 
3、教育经历 
1992.09-1996.06  甘肃农业大学 兽医专业 农学学士
1996.09-1999.06  甘肃农业大学 兽医专业 农学硕士
1999.09-2002.06  东北农业大学 兽医专业 农学博士
 
4、工作经历
2002–2004  中国农业科学院哈尔滨兽医研究所 助理研究员
2004–2013  中国农业科学院哈尔滨兽医研究所 副研究员
2013–今      中国农业科学院哈尔滨兽医研究所 研究员
 
5、承担项目
(1)“十三五” 国家重点研发计划项目:猪病未知病原识别技术研究(2016YFD0500705,2016.07-2020.12),150万元;
(2)“十三五” 国家重点研发计划项目:畜禽重要疫病流行病学数据库和传播风险评估模型构建(2017YFD0500105,2017.07-2020.12),74万元;
(3)“十三五” 国家重点研发计划项目:重大动物源性病原体传入风险评估和预警技术研究(2017YFC1200502,2017.07-2020.06),142万元。
 
6、代表论文与著作
  1. Zhibin Shi , Chunguo Liu , Huanliang Yang , Yan Chen , Hua Liu , Lili Wei , Zaisi Liu , Yongping Jiang , Xijun He , Jingfei Wang*. Fur Seal Feces-Associated Circular DNA Virus Identified in Pigs in Anhui, China. Virologuca Sinica. 2020, 183(1).

  2. Liping Huang, Zhenzhao Sun, Deli Xia, Yanwu Wei, Encheng Sun, Chunguo Liu, Hongzhen Zhu, Haiqiao Bian, Hongli Wu, Li Feng, Jingfei Wang *Changming Liu#. Neutralization Mechanism of a Monoclonal Antibod Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope. J. Virol., 2020, 94(8): 01836-19.

  3. Li L(#), Zhang L(#), Hu Q, Zhao L, Nan Y, Hou G, Chen Y, Han X, Ren X, Zhao Q, Tao H, Sun Z, Zhang G, Wu C(*), Wang J(*), Zhou EM(*). MYH9 Key Amino Acid Residues Identified by the Anti-Idiotypic Antibody to Porcine Reproductive and Respiratory Syndrome Virus Glycoprotein 5 Involve in the Virus Internalization by Porcine Alveolar Macrophages. Viruses. 2019 Dec 29;12(1).

  4. Shinuo Cao, Heming Chen, Xiaohan Liang, Jiawen Fu, Shida Wang, Jun Zheng, Zhaoxia Zhang, Yu Pang, Jingfei Wang, Bang Shen and Honglin Jia. The Sec1/Munc18‐like proteins TgSec1 and TgVps45 play pivotal roles in assembly of the pellicle and sub‐pellicle network in Toxoplasma gondii. Molecular Microbiology (2019) 0(0), 1–14.

  5. Huihui Kong, Shujie Ma, Jingfei Wang, Chunyang Gu, Zeng Wang, Jianzhong Shi, Guohua Deng, Yuntao Guan, Hualan Chen Identification of key amino acids in the PB2 and M1 proteins of H7N9 influenza virus that affect its transmission in guinea pigs. Journal of Virology. doi:10.1128/JVI.01180-19.

  6. Nan Wang, Dongming Zhao, Jialing Wang, Yangling Zhang, Ming Wang, Yan Gao, Fang Li, Jingfei Wang, Zhigao Bu, Zihe Rao, Xiangxi Wang. Architecture of African swine fever virus and implications for viral assembly. Science, DOI:10.1126/science.aaz1439. (2019)

  7. Biyun Xue, Gaopeng Hou, Guixi Zhang, Jingjing Huang, Liangliang Li, Yuchen Nan, Yang Mu, Lizhen Wang, Lu Zhang, Ximeng Han, Xiaolei Ren, Qin Zhao, Chunyan Wu, Jingfei Wang* and En-Min Zhou. MYH9 Aggregation Induced by Direct Interaction with PRRSV GP5 Ectodomain Facilitates Viral Internalization by Permissive Cells. Front. Microbiol. (2019) 10:2313. doi: 10.3389/fmicb.2019.02313.

  8. Longtao Wang, Qiang Liu, Yongli Zhang, Lisi Chen, Shouping Hu, Zhuo Zhang, Jingfei Wang, Xuehui Cai, Honglin Jia, Xijun He. Establishment of BV2 microglia polarization model and its effect on Toxoplasma gondii proliferation, Research in Veterinary Science, 125(2019):382-389. doi.org/10.1016/j.rvsc.2019.08.002.

  9. Gaopeng Hou, Biyun Xue1, Liangliang Li, Yuchen Nan, Lu Zhang, Kuokuo Li, Qin Zhao, Julian A. Hiscox, James P. Stewart, Chunyan Wu, Jingfei Wang* and En-min Zhou. Direct Interaction Between CD163 N-Terminal Domain and MYH9 C-Terminal Domain Contributes to Porcine Reproductive and Respiratory Syndrome Virus Internalization by Permissive Cells. Front. Microbiol. (2019) 10:1815. doi: 10.3389/fmicb.2019.01815. 

  10. Dexing Ma, Yuchen Huang, Chunli,Ma,  Lili Zhang,  Jingfei Wang*, Dian Wang,  Jian Li,  Rami A Dalloul. Eimeria tenella: specific EtAMA1-binding peptides inhibit sporozoite entry into host cells, Poultry Science, 2019, https://doi.org/10.3382/ps/pez298.

  11. Samuel Miño, Laura Mojsiejczuk, Wei Guo, Haili Zhang, Ting Qi, Cheng Du, Xiang Zhang, Jingfei Wang, Rodolfo Campos, Xiaojun Wang. Equine influenza virus in Asia: phylogeographic pattern and molecular features revealed the circulation of an autochthonous lineage. Journal of Virology, Journal of Virology, 2019, doi:10.1128/JVI.00116-19.

  12. Dongming Zhao, Renqiang Liu, Xianfeng Zhang, Fang Li, Jingfei Wang, Jiwen Zhang, Xing Liu, Lulu Wang, Jiaoer Zhang, Xinzhou Wu, Yuntao Guan, Weiye Chen, Xijun Wang, Xijun He & Zhigao Bu. Replication and virulence in pigs of the first African swine fever virus isolated in China, Emerging Microbes & Infections, 2019, 8:1, 438-447, DOI: 10.1080/22221751.2019.1590128.

  13. Mengmeng Yu, Lixiao Xing, Fangfang Chang, Yuanling Bao, Suyan Wang, Xijun He, Jingfei Wang, Shida Wang, Yongzhen Liu, Muhammad Farooque, Qing Pan, Yongqiang Wang, Li Gao, Xiaole Qi, Altaf Hussain, Kai Li, Changjun Liu, Yanping Zhang, Hongyu Cui, Xiaomei Wang, Yulong Gao. Genomic sequence and pathogenicity of the first avian metapneumovirus subtype B isolated from chicken in China. Veterinary Microbiology, 228 (2019) 32–38.

  14. Lihong Chen, Ming Wang, Dongjie Zhu, Zhenzhao Sun, Jun Ma, Jinglin Wang, Lingfei Kong, Shida Wan, Zaisi Liu, Lili We, Yuwen He, Jingfei Wang*, Xinzheng Zhang. Implication for alphavirus host-cell entry and assembly indicated by a 3.5Å resolution cryo-EM structure. Nature Communications, 2018.11.14, 9(5326).

  15. Wang Yongqiang, Duan Yulu, Han Chunyan, Yao Shuai, Qi Xiaole, Gao Yulong, Maier Helena J, Britton Paul, Chen Lei, Zhang Lizhou, Gao Li, Gao Honglei, Shen Nan, Wang Jingfei, Wang Xiaomei. Infectious Bursal Disease Virus Subverts Autophagic Vacuoles to Promote Viral Maturation and Release. Journal of Virology, 2017.03, 91(5): 1-18.

 
7、专利和标准
(1)  王靖飞,王云峰,郭东春,戴有礼,徐志宏,秦卓明,孙卫东,吕殿红,赵秀美,禽病疫情监测系统V1.0,2019SR0723542.
(2) 王靖飞,禽流行病学数据库管理系统V1.0,2015SR038915.
(3) 王靖飞,序列熵值计算软件[简称:Entropy] V1.0.0,2009SR061228;
(4) 王靖飞,鸡疾病诊断数字化智能系统(B/S),2005SR08613;
(5) 王靖飞,鸡疾病防治数字化智能系统(B/S),2005SR08612;
(6) 王靖飞,中国禽流感毒株信息管理系统,2004SR09023.
 
8、获得奖励
(1) 动物疫病风险评估方法的建立及应用,黑龙江省畜牧科技一等奖,第二完成人,2010年; 
(2) 动物疫病风险评估方法的建立及应用,黑龙江省科技进步二等奖,第二完成人,2010年;
(3) 猪瘟、猪繁殖与呼吸综合征、猪伪狂犬病毒抗体三种金标快速检测试纸条等的研制及初步应用,黑龙江省科技进步三等奖,第六完成人,2010年;
(4) 猪瘟、猪繁殖与呼吸综合征、猪伪狂犬病毒抗体三种金标快速检测试纸条等的研制及初步应用,哈尔滨市科技进步二等奖,第六完成人,2009年;

(5) 猪禽等几种重大传染病胶体金快速诊断试纸条的研制,中国农业科学院科学技术成果二等奖,第六完成人,2006年。


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