1、个人简历
曲连东，男，博士，研究员，博士导师，中国农业科学院哈尔滨兽医研究所人兽共患病研究室主任，宠物疫病创新团队资深首席。主要围绕危害养殖业和人类公共卫生的自然疫源性人兽共患病及宠物病原，开展西尼罗河病毒、呼肠孤病毒、杯状病毒、疱疹病毒、冠状病毒、大肠杆菌和巴氏杆菌等病原的监测、生物学、免疫及致病机制等研究，研发宠物病防控制剂。
中国兽药典委员会委员、国家实验动物专家委员会委员、全国实验动物标准化委员会委员。兼任中国实验动物学会常务理事长，中国实验动物学会农业实验动物专业委员主任委员，中国畜牧兽医学会畜牧兽医生物技术分会理事。主持科研课题20余项，获成果奖励6项，出版编著作8部；发表论文80余篇，其中在Sci Rep、J Clin Microbiol、Front Microbiol等期刊发表SCI论文30余篇；授权专利8项，制定国家标准10项，农业行业标准2项，地方标准2项。培养博士研究生和硕士研究生30余名。
Genome-Wide Analyses Reveal Genes Subject to Positive Selection in Pasteurella multocida.Cao P, Guo D, Liu J, Jiang Q, Xu Z, Qu L.Front Microbiol. 2017 May 30;8:961. doi: 10.3389/fmicb.2017.00961. eCollection 2017.
Feline Panleucopenia Virus NS2 Suppresses the Host IFN-β Induction by Disrupting the Interaction between TBK1 and STING.Kang H, Liu D, Tian J, Hu X, Zhang X, Yin H, Wu H, Liu C, Guo D, Li Z, Jiang Q, Liu J, Qu L.Viruses. 2017 Jan 23;9(1). pii: E23. doi: 10.3390/v9010023.
Identification of Inonotus obliquus polysaccharide with broad-spectrum antiviral activity against multi-feline viruses.Tian J, Hu X, Liu D, Wu H, Qu L.Int J Biol Macromol. 2017 Feb;95:160-167. doi: 10.1016/j.ijbiomac.2016.11.054. Epub 2016 Nov 16.
Molecular characterization of a feline calicivirus isolated from tiger and its pathogenesis in cats.Tian J, Liu D, Liu Y, Wu H, Jiang Y, Zu S, Liu C, Sun X, Liu J, Qu L.Vet Microbiol. 2016 Aug 30;192:110-7. doi: 10.1016/j.vetmic.2016.07.005. Epub 2016 Jul 7.
N-Terminal Domain of Feline Calicivirus (FCV) Proteinase-Polymerase Contributes to the Inhibition of Host Cell Transcription.Wu H, Zu S, Sun X, Liu Y, Tian J, Qu L.
Characterization and pathogenicity of a novel mammalian orthoreovirus from wild short-nosed fruit bats.Li Z, Liu D, Ran X, Liu C, Guo D, Hu X, Tian J, Zhang X, Shao Y, Liu S, Qu L.Infect Genet Evol. 2016 Sep;43:347-53. doi: 10.1016/j.meegid.2016.05.039. Epub 2016 May 31.
In vitro antiviral effect of germacrone on feline calicivirus.Wu H, Liu Y, Zu S, Sun X, Liu C, Liu D, Zhang X, Tian J, Qu L.Arch Virol. 2016 Jun;161(6):1559-67. doi: 10.1007/s00705-016-2825-8. Epub 2016 Mar 21.
Production, Characterization, and Epitope Mapping of Monoclonal Antibodies Against Different Subtypes of Rabbit Hemorrhagic Disease Virus (RHDV).Kong D, Liu J, Jiang Q, Yu Z, Hu X, Guo D, Huang Q, Jiao M, Qu L.Sci Rep. 2016 Feb 16;6:20857. doi: 10.1038/srep20857.
Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes.Tian J, Zhang X, Wu H, Liu C, Li Z, Hu X, Su S, Wang LF, Qu L.Front Microbiol. 2015 Sep 2;6:886. doi: 10.3389/fmicb.2015.00886. eCollection 2015.
Isolation and pathogenicity of the mammalian orthoreovirus MPC/04 from masked civet cats.Li Z, Shao Y, Liu C, Liu D, Guo D, Qiu Z, Tian J, Zhang X, Liu S, Qu L.Infect Genet Evol. 2015 Dec;36:55-61. doi: 10.1016/j.meegid.2015.08.037. Epub 2015 Sep 19.
Molecular cloning and functional characterization of feline MAVS.Wu H, Zhang X, Liu C, Liu D, Liu J, Wang G, Tian J, Qu L.Immunol Res. 2016 Feb;64(1):82-92. doi: 10.1007/s12026-015-8682-9.
Antiviral effect of lithium chloride on feline calicivirus in vitro.Wu H, Zhang X, Liu C, Liu D, Liu J, Tian J, Qu L.Arch Virol. 2015 Dec;160(12):2935-43. doi: 10.1007/s00705-015-2534-8. Epub 2015 Aug 5.
PI3K/Akt/p53 pathway inhibits reovirus infection.Zhang X, Wu H, Liu C, Tian J, Qu L.Infect Genet Evol. 2015 Aug;34:415-22. doi: 10.1016/j.meegid.2015.06.008. Epub 2015 Jun 9.
Assessment of the IFN-β response to four feline caliciviruses: Infection in CRFK cells.Tian J, Zhang X, Wu H, Liu C, Liu J, Hu X, Qu L.Infect Genet Evol. 2015 Aug;34:352-60. doi: 10.1016/j.meegid.2015.06.003. Epub 2015 Jun 5.
刘大飞、张洪英、曲连东、刘春国、林欢，用于同时检测猫泛白细胞减少症病毒、猫杯状病毒和猫疱疹病毒1型的多重PCR引物组，ZL201320159199.8
姜骞、曲连东、林欢、刘加森、郭冬春、司昌德，犬瘟热病毒敏感细胞系及其建立方法和应用，ZL201210152860.8
曲连东、姜骞、周洁、陈洪岩、刘家森、李昌文、张洪英、司昌德、刘立奎、韩凌霞、孟庆文，重组犬2型腺病毒转移载体、其构建方法及应用，Zl2007 1 0130090.6
曲连东、韩凌霞、姜骞、刘家森、郭东春、司昌德、于海， SP鸡 微生物学检测总则GB/T-17999.1-12008
无特定病原体鸭的培育及应用，黑龙江省科技进步三等奖，曲连东、韩凌霞、郭东春、刘家森、姜骞、张伟、于海波，2016年
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